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Overview of Clinical NGS DB

Recent advances in next-generation sequencing have given rise to new challenges due to difficulties in variant pathogenicity interpretation and large dataset management, including many kinds of public population databases as well as public or commercial disease-specific databases.

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We developed a new database development tool, named the “Clinical NGS database,” for improving clinical next-generation sequencing workflow through the unified management of variant and clinical information. This database was also intended to assist in efficient variant pathogenicity interpretation by gathering all knowledge about the variant and comparing the clinical features of each patient.

 

This software was designed for non-PC specialists such as wet lab researchers or clinicians and is easy start up and maintain easily.

Simple and User Friendly

Clinical NGS DB is designed to easy start up and easy maintenance for non-PC specialists such as wet lab researchers or clinicians.  

Unified Management

Clinical NGS DB offers a unified management database containing the clinical information and NGS analysis results for a large number of patients.

​Small Computer Load

​Clinical NGS DB uses a relatively small computer load and can be used even on lap-top computers.

Statistical Approach

Clinical NGS DB offers a statistical approach to variant pathogenicity classification that uses the odds ratio for comparisons between the case and the control comparison in each inheritance mode.

Phenotype-Based Approach

In this database, it is easy to compare the detailed phenotypes among patients with the same mutation.

Powerful Search

Another characteristic feature of this software is its powerful search function. You can easily identify patients fulfilling your search terms.

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